Symbiote Supreme enters The Contest October 11th at 10AM PDT!

About Symbiote Supreme:

The result of an unholy union between an alternate reality Doctor Strange and a particularly virulent Klyntar specimen, the entity known as Symbiote Supreme wields an unnatural power thanks to its mastery of Symbiomancy: the ability to summon and control its Symbiote through magical means. The Symbiote Supreme finds and bonds with any lifeform it can, devouring them into its hivemind in order to spread its dark influence across The Battlerealm.

Base Stats & Abilities

*All stats based on 4-Star, Rank 5, Level 50, Signature Level 99

Health:  13379

Attack:  1092

Max PI:

  • Without Signature: 3833
  • With Signature (99): 4769

*All stats based on 5-Star, Rank 5, Level 65, Signature Level 200

Health:  26826

Attack:  2189

Max PI:

  • Without Signature: 7720
  • With Signature (200): 10540

Basic Abilities: Armor, Fury, Nullify, Power Drain

Character Class: Mystic


  • Symbiote Supreme gains 100% less power from Attacking, Blocking, and being Struck. But gains 16.5% of his Max Power every 9 seconds.

Developer Note: This is slower (about half) the rate that Doctor Strange gains power, but Symbiote Supreme makes up for this difference with his Genetic Potential Power Gain.

Genetic Potential – Passive

  • Each time a Buff or a Stagger effect on the Opponent ends gain 25 Genetic Potential, to a maximum of 100.
  • Gain an additional 50 Genetic Potential if a Buff ends due to a Nullify or Stagger effect.

Genetic Blessings – Passive

  • Symbiote Supreme can manifest 3 different Genetic Blessings, every 15 seconds he switches to the next in the following order: Chthon’s Cunning, Null’s Shadow, and Set’s Fangs.
  • Each time a Blessing triggers 100% of Genetic Potential is consumed to gain up to 100% of a Bar of Power.

Developer Note: This is the Power Gain which compensates for the lower base Power Gain speed compared to Doctor Strange. A full 100 Genetic Potential is worth a full bar of Power when the new Blessing triggers!

Chthon’s Cunning – Passive

  • 100% chance when this Blessing is triggered to immediately Nullify all Buffs off the Opponent.
  • 709.8 Direct Damage is Passively dealt to the Opponent for each Buff Nullified, based on Genetic Potential.
  • While active gain a 5% chance to place a Stagger Passive on the Opponent lasting 10 seconds on each Basic Attack Hit. Critical Hits increase the Chance to 50%.

Developer Note: The “Anti-Buff” Blessing. Symbiote Supreme always starts with this Blessing active, so he’ll remove whatever Buffs you have on you right at the start of the fight dealing damage.

Null’s Shadow – Passive

  • 100% chance when this Blessing is triggered to gain a Protection Buff preventing Symbiote Supreme from taking more than 15% of his Max Health per hit, lasting 10 for seconds. This Protection threshold reduced by 50% if the Opponent has an active Buff.
  • 1333.33 Armor and 40% chance to Perfect Block as a Passive effect, based on Genetic Potential.
  • Gain a 15% chance to place a Stagger Passive on the Opponent lasting 10 seconds each time Symbiote Supreme is Struck by or Blocks the Opponent. Well timed blocks increase the Chance to 100%.

Developer Note: The “Defence” Blessing. With a damage cap, and a Armor and Perfect Block it’s the Blessing to have if you need to tank some hits, and one to avoid throwing huge specials at.

Set’s Fangs – Passive

  • 100% chance when this Blessing is triggered to gain a Fury Buff increasing Attack by up to 1119.3 for 10 Seconds, based on Genetic Potential.
  • 100% chance to cause a Bleed Debuff on every Hit, dealing up to 928.2 Direct Damage based on Genetic Potential and lasting 8 seconds.
  • Each hit of a Special Attack gains a 50% chance to place a Stagger Passive on the Opponent lasting 10 seconds.

Developer Note: The “Offense” Blessing. This is the Blessing to spend your time in if you’re looking to do as much damage as possible.

Special 1 – Grasping Tendrils:

A portal opens to an unknowable dimension, allowing tendrils from beyond to strike.

  • 100% Chance to Nullify 1 Buff. Gain 50 Genetic Potential if a Buff is Nullified.
  • Switch to the next Blessing.

Developer Note: This Special gives Symbiote Supreme some on-demand Nullify Utility as well as a way to help him control which Blessing he spends most of his time in, it can also help him adjust which Special Attack he’ll have immediately available under each Blessing.

Special 2 – Dark Triumvirate:

Symbiote Supreme’s composition of dark power erupts forth from the very ground beneath the enemy’s feet.

  • While Chthon’s Cunning is active each hit has a 100% chance to steal 15% of the Opponent’s Max Power.
  • While Null’s Shadow is active each hit has a 100% chance to place a Weakness Debuff on the Opponent reducing their Attack by 33% for 10 seconds.
  • While Set’s Fangs is active each hit has a 100% chance to place an Armor Break Debuff on the Opponent reducing their Armor by 2000 for 10 seconds..

Special 3 – Dimensional Hunger:

When the hivemind hungers Symbiote Supreme offers up his opponent to sate its desires, if only briefly.

  • 100% chance to reset the Genetic Blessing timer, and active all 3 Genetic Blessings.
  • +100 Genetic Potential.

Developer Note: A way for Symbiote Supreme to activate all of his Blessings at once. Clever use of the Special 3 will allow Symbiote Supreme to spend pretty much double time in one mode, can also function as a panic Nullify button.

Signature Ability: Symbiomancy

The unique combination of Symbiote and mystic arts that power Symbiote Supreme have a disrupting effect on many abilities of the lesser beings inhabiting the Battlerealm.

  • Every 12.51 seconds place a Stagger Passive effect on the Opponent, lasting 10 seconds. Stagger will immediately Nullify the next Buff triggered on the Opponent.

Developer Note: With Staggers being very important to his Power Gain, this helps supercharge Symbiote Supreme’s loop, as well as giving him even better Buff Control, especially if he needs to stop attacking his Opponent to bait a special or avoid a specific ability.

Synergy Bonuses

Mystic Masters – Doctor Strange, Mordo – Unique Synergy

  • Symbiote Supreme: Begin the fight with 1 bar of Power.
  • Doctor Strange:  Deal 50% of Base Attack as Direct Damage when Nullifying a Buff off the Opponent.
  • Mordo: Gain +15% of Base Attack as a Passive Attack bonus while the Opponent is under a Buff effect.

Ancient Hunger – Dormammu, Mephisto – Unique Synergy

  • Symbiote Supreme: Special 2 effects trigger through Blocks.
  • Dormammu: Increases Health Regenerated by an Empowered Soul Bond by 50%.
  • Mephisto: 15% Chance to trigger Aura of Incineration on Basic Attack Hits.

Supreme Symbiosis – Venom, Carnage, Agent Venom, Venom the Duck, Spiderman(Symbiote) – Unique Synergy

  • Symbiote Supreme: Each time a Stagger’s Duration Expires, it has a 25% chance to re-apply itself.
  • Symbiotes: Increases the Duration of all Bleed Effects by 20%.

Recommended Masteries

Mystic Dispersion

  • Symbiote Supreme has several different ways to Nullify/Stagger Buffs from his Opponents, making him an ideal candidate for Mystic Dispersion.

Deep Wounds

  • While under the effects of Set’s Fangs, Symbiote Supreme can cause some pretty significant Bleed damage, Deep Wounds helps push this damage even further.


  • The bonus Attack pays dividends in multiple ways, increasing Set’s Fang’s Fury and Bleed Effects, increase the Chthon’s Cunning Nullify Damage, plus all the natural Assassin goodness.

Strong Matchups

Corvus Glaive

  • The Chthon’s Cunning Nullify will strip away Corvus’s Cruelty and True Damage Buffs right at the beginning of the fight, significantly cutting his damage potential, and taking a chunk out of his health bar right at the beginning of the fight.


  • Medusa’s greatest defensive strength is her auto-block, but since it’s locked behind her Fury Buffs, with all of his Nullify and Stagger Symbiote Supreme likely won’t even have to care about it.


  • Like the Classic Doctor Strange, Symbiote Supreme also deals Energy Damage with his Basic Attacks giving him a solid edge against everyone’s favorite revolutionary.

Weak Matchups

Omega Red

  • Since Omega Red doesn’t trigger Buffs to be taken away and power Genetic Potential, combined with you not wanting to make him Bleed, he’s not a good matchup for Symbiote Supreme.


  • Ultron is one of the worst matchups for Symbiote Supreme. He can’t Bleed taking a big edge off of Set’s Fangs, then since he Regenerates a portion of Energy Damage taken Symbiote Supreme is really going to struggle to make his Damage stick.


  • To fight Wasp effectively, you need to either suppress her Evade with an ability of your own, or play around the window in which it naturally shuts off. Symbiote Supreme can’t do option 1, and which his own rotating Blessings and tendency towards power spikes and troughs, it will be difficult to align Supreme’s moments of max power, with Wasps moments of vulnerability.